Nature's Chemist® is 100% natural and contains no artificial ingredients. Its formula combines maximum strength menthol for pain relief with all natural essentials oils and natural extracts. Menthol, the pain relieving ingredient in Nature's Chemist is at The Maximum strength allowed over the counter. It penetrates deeply and works fast to relieve pain. Major clinicial research study conducted at the Bennett Institute for Sports Medicine and Rehabilitation by a physician and faculty member of The John Hopkins University showed that Nature's Chemist reduces arthritis pain in advanced cases by an average of 67%.